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Jim O'Neill, a top deputy to Health Secretary Robert F. Kennedy Jr., will serve as acting director of the Centers for Disease Control and Prevention. That's according to an administration official who requested anonymity to discuss a personnel change that had not been formally announced Thursday. White House press secretary Karoline Leavitt says CDC Director Susan Monarez was fired by President Donald Trump late Wednesday. Leavitt says Monarez wasn’t “aligned with the president’s mission” and refused to resign. Monarez’s lawyers say she was targeted for standing up for science. Four other agency leaders resigned Wednesday.

Attorney General Pam Bondi has named the head of the Drug Enforcement Administration, Terry Cole, as Washington’s “emergency police commissioner." She says she is granting him the powers of the police chief and that the Metropolitan Police Department “must receive approval from Commissioner Cole” before issuing any orders. The Thursday evening directive follows President Donald Trump’s unprecedented announcement that his administration would take over the D.C. police department and dispatch the National Guard for at least a month. The White House says there will be a round-the-clock presence of local and federal law enforcement officers in the nation's capital.

Some of the 800 National Guard members deployed by the Trump administration to assist with law enforcement have begun arriving in Washington, D.C. The city’s police and federal officials took the first steps Tuesday in an uneasy partnership to reduce crime in what President Donald Trump called — without substantiation — a lawless city. Mayor Muriel Bowser pledged to work alongside the federal officials Trump has tasked with overseeing the capital city’s law enforcement. Bowser insists the police chief remains in charge of the department and its officers. White House press secretary Karoline Leavitt said about 850 officers and agents fanned out across Washington on Monday and arrested 23 people overnight.